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Panel Content Smart Panel Design Performance The Power of More Related Products

Uncover 30 Tumor Markers in a Single Experiment

 

As part of our family of BD® OMICS-One Protein Panels for deep immune discovery experiments, the BD® OMICS-One Tumor Protein Panel is designed with 30 key specificities that will help you profile major tumor cell populations and their features.

 

Designed and optimized for the BD Rhapsody™ Single-Cell Analysis System, the BD® OMICS-One Tumor Protein Panel works seamlessly with single-cell RNA assays in the BD Rhapsody™ System family to enable CITE-seq studies.

 

If you’re interested in single-cell protein-only profiling studies, BD® OMICS-One Protein Panels also support a protein-only workflow.
 

Talk to one of our specialists about bringing this panel to your lab for either CITE-seq or protein-only studies.


Download the BD® OMICS-One Tumor Protein Panel flyer 

 

Explore Tumor Cell Populations and Their Features in Your Samples of Interest

Panel Features

Panel Content

BD® OMICS-One Tumor Protein Panel Content

 

30 pre-titrated antibody-oligos
SpecificityClone
CD24ML5
CD26M-A261
CD29MAR4
CD31 (PECAM-1)WM59
CD34581
CD44*L178
CD45*HI30
CD47B6H12
CD54HA58
CD581C3
SpecificityClone
CD117YB5.B8
CD133W6B3C1
CD146P1H12
CD155TX24
CD227 (MUC1)HMFG2
CD66B1.1/CD66
CD905E10
CD274 (PD-L1)MIH1
CD279 (PD-1)EH12.1
CD324 (E-Cadherin)67A4
SpecificityClone
CD325 (N-Cadherin)8C11
CD326 (EpCAM)EBA-1
c-MET3D6
EGFREGFR,1
EphB22H9
HLA-A,B,C*G46-2.6
Integrin β7FIB504
Notch 1MHN1-519
PodoplaninLpMab-17
VistaMIH65.rMAb

*SMART-titrated targets


Not the panel you are looking for? Explore other available panels

Smart Panel Design

Lower Sequencing Cost and Increase Sensitivity with SMART Panel Design

SMART panel design helps lower sequencing costs while increasing data resolution by using pretitrated, optimal concentrations of antibody-oligos against select high-expressing primary markers in the panel. This allows reallocation of sequencing reads otherwise allotted to these high expressors to now detect secondary and tertiary cell surface markers expressed at lower levels. With the SMART panel design approach, low-expression markers can be quantified without having to perform deeper sequencing and incurring high sequencing costs. The three specificities selected for SMART panel design in the BD® OMICS-One Tumor Protein Panel are CD44, CD45 and HLA-A,B,C.

CD44, CD45 and HLA detection is not compromised

CD44, CD45 and HLA-A,B,C detection is not compromised with SMART panel design

Lowly expressed markers are detected at better resolution

Lowly expressed markers are detected at better resolution with SMART panel design

  

Percent of Total Sequencing Reads Consumed
SpecificityWithout SMART panel designWith SMART panel design
Reduction of sequencing reads allocated to primary markers ↓
CD4435.4719.23
HLA-A,B,C18.4115.14
CD4510.485.03
Read re-allocation to lowly expressed markers ↑
CD547.8314.72
CD474.584.68
CD343.464.13
EGFR2.043.64
CD582.023.00
CD661.752.70
CD2791.652.69
Podoplanin1.242.54
CD1551.132.04
CD241.002.04
CD290.841.78
SpecificityWithout SMART panel designWith SMART panel design
CD310.841.70
CD2740.791.67
CD1170.781.62
CD260.751.58
CD324 0.731.54
Notch10.731.46
CD2270.661.24
EphB20.521.15
CD900.470.96
Integrin β7 0.430.90
c-MET0.370.70
CD3260.320.67
Vista0.300.60
CD1330.200.38
CD3250.190.37
CD1460.040.13

  

Performance

Comparable performance of the lyophilized panel to freshly pooled BD® AbSeq Antibody-Oligo Reagents

The BD® OMICS-One Tumor Protein Panel consists of 30 different specificities against major tumor and immune interaction protein markers in a single tube. Our lyophilized panel yields data comparable with a freshly prepared mixture of the same 30 specificities of BD® AbSeq Antibody-Oligo Reagents.
Lyophilized Panel and BD AbSeq Antibody Oligo Performance Comparison
Lyophilized Panel and BD AbSeq Antibody Oligo Performance Comparison
Reliable performance—detect 30 critical tumor-associated protein markers in your samples with confidence

Ensuring optimal performance of antibodies when multiple specificities are brought together in a panel is critical for protein-profiling studies. We tested the performance of the individual antibody-oligos included in the BD® OMICS-One Tumor Protein Panel and demonstrated that all 30 antibody-oligos reliably detect their respective targets.
Tumor Associated Marker Detection
Tumor Associated Marker Detection
Scalable—add additional antibody-oligos of interest to the BD® OMICS-One Tumor Protein Panel without compromising performance

We recognize there might be instances where critical markers important for your studies may not be covered by our pre-made panels. Keeping this in mind, BD® OMICS-One Protein Panels are designed to accommodate drop-in BD® AbSeq Antibody-Oligos of your choice.
No Performance Compromize with Added Antibody Oligos
No Performance Compromize with Added Antibody Oligos
Multiomics compatible—combine the BD® OMICS-One Tumor Protein Panel with RNA and TCR/BCR profiling assays

BD® OMICS-One Protein Panels are designed keeping multiomics in mind. These protein panels work seamlessly with BD Rhapsody™ Single-Cell Whole Transcriptome and TCR/BCR Profiling Assays.

The Power of More

A Smart Platform for Your SMART Protein Panels

With our complete solution you can now explore more omes in one data readout. Get more quality data and more breakthroughs, all at less than 1 cent per cell*.

 

Explore how you can harness the POWER OF MORE with the only complete single-cell multiomics solution.

 

The Complete Single Cell Multiomics Solution
*1 cent per cell calculation includes instruments and reagents but is not inclusive of sequencing costs.

Request a Consultation

Want to learn more about BD® OMICS-One Protein Panels or our single-cell multiomics solution?

 

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BD® OMICS-One B-Cell Protein Panel BD® OMICS-One T-Cell Protein Panel BD® OMICS-One Immune Profiler Panel BD® OMICS-One Adaptive Protein Panel BD® OMICS-One Immuno-Oncology Protein Panel
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