Blood Collection Solutions
The BD Vacutainer® and PAXgene® Cell and Biomarker Preservation Tubes stabilize biomarkers from discovery to clinical results.
The BD Vacutainer family of products for cell and biomarker preservation are widely used in clinical and biomarker research across the world, in conjunction with a variety of downstream molecular, proteomic and cellular applications.
The Trusted Name in Biomarker Stabilization
Sample collection is the first step in the workflow for development of new therapies and it is important to ensure a reliable sample collection process for obtaining accurate downstream analytical results. For over 70 years, BD has been a trusted name for blood specimen management solutions. The BD Vacutainer® family of products for blood cell and biomarker preservation are widely used in clinical and biomarker research across the world, in conjunction with a variety of downstream molecular, proteomics and cellular applications. These products can help ensure consistency in results, accuracy of data and workflow efficiency when measuring biomarkers.
Choose from a variety of cell and biomarker preservation tubes designed for your specific downstream molecular, proteomics and cellular application.
Choose from a variety of cell and biomarker preservation tubes designed for your specific downstream molecular, proteomics and cellular application.
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| BD Vacutainer® CPT™ Mononuclear Cell Preparation Tube (IVD) | PreAnalytiX PAXgene® Blood RNA Tube (IVD) | PreAnalytiX PAXgene® Blood DNA Tube (IVD) | BD Vacutainer® PPT™ Plasma Preparation Tube (IVD) | BD™ P800 Blood Collection System (RUO) | BD™ P100 Blood Collection System (RUO) | PAXgene Blood ccfDNA Tube (CE-IVD) | |
| Common Applications | Cellular in vitro assays | Gene expression analysis | In vitro diagnostic DNA testing | Molecular testing of infectious diseases | Stabilization of select metabolic markers | Plasma protein stabilization | Molecular testing of ccfDNA or gDNA |
| Description | A closed system for separation of mononuclear cells (PBMCs) from whole blood. | Immediate stabilization of intracellular RNA, thereby yielding accurate and reproducible gene expression data. | The first blood collection tube specifically designed for in vitro diagnostic DNA testing (collect, anticoagulate, stabilize, transport, and store a venous whole blood sample for preparation of DNA). | A closed system for separation and storage of undiluted EDTA plasma in the primary blood collection tube for molecular diagnostic testing. | Stabilization of metabolic markers such as Glucagon-Like Peptide-1 (GLP-1), Glucagon, non-acyl Ghrelin, Gastric Inhibitory Polypeptide (GIP), and Oxyntomodulin (OXM) at the point of collection. | Stabilization of human plasma proteins at the point of collection to minimize preanalytical variability in plasma protein analysis. | Intended for collection, storage, and transport of human blood and stabilization of DNA in a closed tube for preparation of circulating, cell-free DNA (ccfDNA) from plasma and genomic DNA (gDNA) from nucleated cellular fraction, for use with molecular test methods that require ccfDNA or gDNA. |
| Regulatory Status | IVD | IVD | IVD | IVD | RUO | RUO | IVD |
| Available Configurations | Sodium Heparin 16x125 mm / 8 mL 362753 Sodium Citrate 13x100 mm / 4 mL 362760 Sodium Citrate 16x125 mm / 8 mL 362761 | 16x100 mm / 2.5 mL 762165 | 13x75 mm / 2.5 mL 761165 | 13x100 mm / 5 mL 362788 16x100 mm / 8.5 mL | 13x75 mm / 2 mL 366420 16x100 mm / 8.5 mL 366421 | 13x75 mm / 2 mL 366422 16x100 mm / 8.5 mL 366448 | 16X100 mm / 10mL, 768165 |
Why Is Reliable Sample Collection Important?
- First step in ensuring accurate downstream analytical results
- Reliable sample collection is essential for the development of new therapies
Common Applications of the BD Vacutainer and PAXGene® Cell and Biomarker Preservation Tubes
- Blood Transcriptome profiling and response of pandemic patients
- The PAXgene® RNA Blood Collection Tube provides a robust proprietary reagent that immediately stabilizes RNA, with continued evidence to show that the integrity of RNA is not compromised even if stored frozen for at least 11 years.
- The BD Vacutainer® Cell Preparation Tube (CPT) is designed to simplify PBMC extraction, remove the variability due to manual gradient techniques, reduce consumables, and ensure that sampling is consistent for challenging collection environments.
- Immunology research
- Stable RNA collection for molecular in-vitro diagnostic testing and gene expression profiling
- Circulating cell-free DNA (ccfDNA) integrity maintenance and liquid biopsy workflow
- Accurate RNA profiles from cancer cells
Publications using the BD Vacutainer and PAXGene® Cell and Biomarker Preservation Tubes
The following studies demonstrate the utility of PAXgene® Blood RNA and BD CPT™ products for research in the fight against the pandemic.
- Whole-blood transcriptomic host response to the pandemic virus
- Multidimensional precision medicine transcriptional workflow
- Differential microRNA expression
- Early marker for severe pandemic cases: Neutrophil-to-VD2 T-cell ratio
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