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Trained immunity or innate immune memory is the property of innate immune cells to adapt the host responses to mount resistance to past intruders.14 The response is still less specific than adaptive immune memory but can allow broad recognition of classes of pathogens such as Gram-positive and Gram-negative bacteria through the involvement of different types of pattern recognition receptors (PRRs).
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Trained immunity or innate immune memory is the property of innate immune cells to adapt the host responses to mount resistance to past intruders.14 The response is still less specific than adaptive immune memory but can allow broad recognition of classes of pathogens such as Gram-positive and Gram-negative bacteria through the involvement of different types of pattern recognition receptors (PRRs).
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The BD Rhapsody™ HT Single-Cell Analysis System enables single-cell capture with reliable and reproducible results with minimal site-to-site variability making it suitable for translational, multi-center, multi-cohort studies. One readout can be used to analyze both protein and mRNA, reducing experimental time and increasing information derived from a single experiment. BD® AbSeq Antibody-Oligonucleotide Conjugates allows high-parameter protein expression data simultaneously with single-cell RNA-Seq data to significantly improve your understanding of individual cells. For example, targeted panels like the BD Rhapsody™ TCR/BCR Multiomic Assay Kit allow protein and whole transcriptome mRNA analysis to comprehensively understand immune cell function. Using genomic and proteomic information from single-cell analysis, you can concentrate on cells of interest for a deeper understanding. The BD FACSymphony™ S6 Cell Sorter enables sorting of populations by using up to 50 parameters to define populations deep in your gating hierarchy. The detection technology in the BD FACSymphony™ A5 SE Cell Analyzer has enhanced resolution across the visible spectrum to identify and analyze rare cell types.
Learn more about the single-cell multiomics approach to comprehensively identify the gene and protein signature of T-cells.
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Customizable end-to-end solutions with workflow flexibility for multiomic and single-cell analysis
The BD FACSymphony™ Cell Analyzers leverage the benefits of high-parameter flow cytometry for simultaneous measurements, depending on the system, of up to 50 different characteristics of a single cell, accommodating your workflow needs. The BD FACSymphony™ A5 SE Cell Analyzer offers flexibility with an optical design that enables both spectral unmixing and compensation workflows. Our broad array of flow cytometry reagents including BD Horizon Brilliant™ Dyes, and BD Horizon RealYellow™ and BD Horizon RealBlue™ Fluorochromes with more than 9,000 human immunology research reagents can support cell therapy research. Made on demand, the BD OptiBuild™ Reagents also provide lot-to-lot consistency that can be tailored to your requirements. At your disposal is a wide range of custom products including BD® Abseq Reagents, instruments, conjugates, multicolor panels and cocktails to fit your needs.
BD products provide unique customizable end-to-end solutions with workflow flexibility for multiomic analysis and single-cell isolation of specific, rare cell populations. Led by you for your specific purpose, our team of scientists and experts can help with panel design, reagent selection, assay implementation, workflow optimization and experimental troubleshooting.
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The BD Rhapsody™ HT Single-Cell Analysis System enables single-cell capture with reliable and reproducible results with minimal site-to-site variability making it suitable for translational, multi-center, multi-cohort studies. One readout can be used to analyze both protein and mRNA, reducing experimental time and increasing information derived from a single experiment. BD® AbSeq Antibody-Oligonucleotide Conjugates allows high-parameter protein expression data simultaneously with single-cell RNA-Seq data to significantly improve your understanding of individual cells. For example, targeted panels like the BD Rhapsody™ TCR/BCR Multiomic Assay Kit allow protein and whole transcriptome mRNA analysis to comprehensively understand immune cell function. Using genomic and proteomic information from single-cell analysis, you can concentrate on cells of interest for a deeper understanding. The BD FACSymphony™ S6 Cell Sorter enables sorting of populations by using up to 50 parameters to define populations deep in your gating hierarchy. The detection technology in the BD FACSymphony™ A5 SE Cell Analyzer has enhanced resolution across the visible spectrum to identify and analyze rare cell types.
Learn more about the single-cell multiomics approach to comprehensively identify the gene and protein signature of T-cells.
image caption
Customizable end-to-end solutions with workflow flexibility for multiomic and single-cell analysis
The BD FACSymphony™ Cell Analyzers leverage the benefits of high-parameter flow cytometry for simultaneous measurements, depending on the system, of up to 50 different characteristics of a single cell, accommodating your workflow needs. The BD FACSymphony™ A5 SE Cell Analyzer offers flexibility with an optical design that enables both spectral unmixing and compensation workflows. Our broad array of flow cytometry reagents including BD Horizon Brilliant™ Dyes, and BD Horizon RealYellow™ and BD Horizon RealBlue™ Fluorochromes with more than 9,000 human immunology research reagents can support cell therapy research. Made on demand, the BD OptiBuild™ Reagents also provide lot-to-lot consistency that can be tailored to your requirements. At your disposal is a wide range of custom products including BD® Abseq Reagents, instruments, conjugates, multicolor panels and cocktails to fit your needs.
BD products provide unique customizable end-to-end solutions with workflow flexibility for multiomic analysis and single-cell isolation of specific, rare cell populations. Led by you for your specific purpose, our team of scientists and experts can help with panel design, reagent selection, assay implementation, workflow optimization and experimental troubleshooting.