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The immune system provides surveillance and protection from pathogenic invaders and prevents detrimental responses against the self that could lead to autoimmunity. Alterations or dysregulations of components of the immune system, be it in the immune cells or their signaling pathways, can cause either low- (immune deficiency) or hyper-activity (autoimmunity) of the immune system.
Complete blood count (CBC) test, which is often part of routine/annual checkup, does not provide granular information at the lymphocyte level. Flow cytometry is widely used to gain deeper insights into immune cell populations through immunophenotyping for disease-specific assessments.
We offer a range of reagents, such as BD Multitest™reagents with optional BD Trucount™ Tubes, that are intended for use in the immunological assessment of normal individuals and patients having, or suspected of having, immune deficiency. Together with instrumentation and software, they provide a complete IVD solution for immunological assessment.
All BD Multitest™ Reagents integrate seamlessly with our BD FACSLyric™ Flow Cytometer and FACSDuet™ Sample Preparation System that streamlines your lab workflow through flexibility and automation, boosting efficiency and productivity. BD FACSuite™ Multitest assay modules provide predefined instrument settings and premade templates with gating algorithms for acquisition and analysis that simplifies the overall workflow.
The FACSLyric™ Flow Cytometer with FACSDuet™ Sample Preparation System provides a complete IVD walkaway sample-to-answer solution, eliminating hands-on time for preparation. The system is designed to complement and physically integrate with the BD FACSLyric™ Flow Cytometer to drive productivity and accuracy in your results through its automation protocol, minimizing manual intervention. The BD FACSLyric™ Flow Cytometer comes with the BD FACSuite™ and BD FACSuite™ Clinical Applications for sample acquisition and data analysis. Both applications include password protection, audit trail, electronic signatures and IQ/OQ procedures, assisting in supporting 21 CFR Part 11 compliance and electronic record integrity.
| SKU | Product | Total T Cells | T Helper Cells | T Cytotoxic Cells | NK Cells | B Cells | Absolute Counts |
|---|---|---|---|---|---|---|---|
| 662967 | BD Multitest™ 6-Color TBNK Reagents | X | X | X | X | X | |
| 662995 | BD Multitest™ 6-Color TBNK Reagents with BD Trucount™ Tubes | X | X | X | X | X | X |
| 662965 | BD Multitest™ IMK Kit | X | X | X | X | X | |
| 662966 | BD Multitest™ IMK Kit with BD Trucount™ Tubes | X | X | X | X | X | X |
| 340499 | BD Multitest™ CD3/CD8/CD45/CD4 | X | X | X | |||
| 340500 | BD Multitest™ CD3/CD16+ /CD56/CD45/CD19 | X | X | X | |||
| 340334 | BD Trucount™ Troucount Absolute Counting Tubes IVD | X |
Human immunodeficiency virus (HIV) infection results in the depletion of CD4+ T-cell population through various mechanisms.1 Viral load monitoring and CD4 T-cell count are routinely used for HIV monitoring. CD4 T-cell count measurements are critical for gaining insights into HIV disease progression.1
Flow cytometry is a standard technique used for determining CD4 counts as it provides accuracy, precision and reproducibility. Both percentage CD4+ T-lymphocytes among lymphocytes and absolute lymphocyte counts can be determined using flow cytometry. 2
We offer various clinical CD4 testing solutions, including a fully automated clinical flow cytometer, sample preparation reagents and software.
The FACSLyric™ Flow Cytometer streamlines your lab workflow through flexibility and automation, enabling efficiency and productivity.
The BD FACSuite™ Clinical Application with predefined templates for 4-color BD Multitest™ Reagent and 6-color TBNK analysis, provides reproducible and consistent results.
It works with the FACSLyric™ Flow Cytometer for acquisition and analysis, supporting many functions and options relevant to U.S. FDA 21 CFR Part 11 compliance, including password protection, audit trail, electronic signatures and IQ/OQ procedures.
Universal setup is an automated system that establishes and maintains instrument MFI target values on a single instrument using the BD FACSuite™ Clinical Application, BD® CS&T Beads and BD® FC Beads, allowing for reproducible and consistent results within and between BD FACSLyric™ instruments over time. These settings can be easily transferred from instrument-to-instrument via the BD FACSuite™ Clinical Application assay export and transfer feature automating standardization and enabling collaboration across sites.
All BD Multitest™ Reagents integrate seamlessly with our BD FACSLyric™ Flow Cytometer and FACSDuet™ Sample Preparation System that streamlines your lab workflow through flexibility and automation, boosting efficiency and productivity. BD FACSuite™ Multitest assay modules provide predefined instrument settings and premade templates with gating algorithms for acquisition and analysis that simplifies the overall workflow.
The FACSLyric™ Flow Cytometer with FACSDuet™ Sample Preparation System provides a complete IVD walkaway sample-to-answer solution, eliminating hands-on time for preparation. The system is designed to complement and physically integrate with the BD FACSLyric™ Flow Cytometer to drive productivity and accuracy in your results through its automation protocol, minimizing manual intervention. The BD FACSLyric™ Flow Cytometer comes with the BD FACSuite™ and BD FACSuite™ Clinical Applications for sample acquisition and data analysis. Both applications include password protection, audit trail, electronic signatures and IQ/OQ procedures, assisting in supporting 21 CFR Part 11 compliance and electronic record integrity.
| SKU | Product | Total T Cells | T Helper Cells | T Cytotoxic Cells | NK Cells | B Cells | Absolute Counts |
|---|---|---|---|---|---|---|---|
| 662967 | BD Multitest™ 6-Color TBNK Reagents | X | X | X | X | X | |
| 662995 | BD Multitest™ 6-Color TBNK Reagents with BD Trucount™ Tubes | X | X | X | X | X | X |
| 662965 | BD Multitest™ IMK Kit | X | X | X | X | X | |
| 662966 | BD Multitest™ IMK Kit with BD Trucount™ Tubes | X | X | X | X | X | X |
| 340499 | BD Multitest™ CD3/CD8/CD45/CD4 | X | X | X | |||
| 340500 | BD Multitest™ CD3/CD16+ /CD56/CD45/CD19 | X | X | X | |||
| 340334 | BD Trucount™ Troucount Absolute Counting Tubes IVD | X |
Human immunodeficiency virus (HIV) infection results in the depletion of CD4+ T-cell population through various mechanisms.1 Viral load monitoring and CD4 T-cell count are routinely used for HIV monitoring. CD4 T-cell count measurements are critical for gaining insights into HIV disease progression.1
Flow cytometry is a standard technique used for determining CD4 counts as it provides accuracy, precision and reproducibility. Both percentage CD4+ T-lymphocytes among lymphocytes and absolute lymphocyte counts can be determined using flow cytometry. 2
We offer various clinical CD4 testing solutions, including a fully automated clinical flow cytometer, sample preparation reagents and software.
The FACSLyric™ Flow Cytometer streamlines your lab workflow through flexibility and automation, enabling efficiency and productivity.
The BD FACSuite™ Clinical Application with predefined templates for 4-color BD Multitest™ Reagent and 6-color TBNK analysis, provides reproducible and consistent results.
It works with the FACSLyric™ Flow Cytometer for acquisition and analysis, supporting many functions and options relevant to U.S. FDA 21 CFR Part 11 compliance, including password protection, audit trail, electronic signatures and IQ/OQ procedures.
Universal setup is an automated system that establishes and maintains instrument MFI target values on a single instrument using the BD FACSuite™ Clinical Application, BD® CS&T Beads and BD® FC Beads, allowing for reproducible and consistent results within and between BD FACSLyric™ instruments over time. These settings can be easily transferred from instrument-to-instrument via the BD FACSuite™ Clinical Application assay export and transfer feature automating standardization and enabling collaboration across sites.
Representative data from a sample acquired using BD Trucount™ Tubes. See the BD FACSLyric™ Clinical Reference System, which provides information on gating and troubleshooting.
Representative data from a hematologically normal adult sample stained with BD Multitest CD3/CD16+CD56/CD45/CD19 in a BD Trucount™ Tube (BD FACSLyric™ Flow Cytometer).
A streamlined methodology for immunological assessment of patients having or suspected of having an immune deficiency such as HIV using the BD FACSLyric™ Flow Cytometry System.
