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BD Rhapsody™ Human Immune Response Panel
(RUO)
Regulatory Status Legend
Any use of products other than the permitted use without the express written authorization of Becton, Dickinson and Company is strictly prohibited.
Description
This panel contains primer pairs that target 399 genes commonly expressed in human immune cells. The primer pairs have been validated for use in BD Rhapsody™ targeted assays.
Preparation And Storage
Store primer sets at –25°C to –15°C.
Development References (10)
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Alivernini S, MacDonald L, Elmesmari A, et al. Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nat Med. 2020; 26(8):1295-1306. (Methodology). View Reference
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Arroyo Hornero R, Georgiadis C, Hua P, et al. CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells. Commun Biol. 2020; 3(1):375. (Methodology). View Reference
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Ferreira RC, Castro Dopico X, Oliveira JJ, et al. Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression. Front Immunol. 2019; 10:2606. (Methodology). View Reference
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Gertz ML, Chin CR, Tomoiaga D, et al. Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity. Cell Rep. 2020; 33(10):108429. (Methodology). View Reference
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Malkani S, Chin CR, Cekanaviciute E, et al. Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development. Cell Rep. 2020; 33(10):108448. (Methodology). View Reference
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Sainson RCA, Thotakura AK, Kosmac M, et al. An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression. Cancer Immunol Res. 2020; 8(12):1568-1582. (Methodology). View Reference
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See BD Rhapsody&trade. Immune Response Targeted Panel (Human) brochure referenced in BD Genomics Resource Library. (Biology).
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Trzupek D, Dunstan M, Cutler AJ, et al. Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis. Genome Med. 2020; 12(1):55. (Methodology). View Reference
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Wagar LE, Salahudeen A, Constantz CM, et al. Modeling human adaptive immune responses with tonsil organoids. Nat Med. 2021; 27(1):125-135. (Methodology). View Reference
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Yang Y, Liu F, Liu W, et al. Analysis of single-cell RNAseq identifies transitional states of T cells associated with hepatocellular carcinoma. Clin Transl Med. 2020; 10(3):e133. (Methodology). View Reference
Please refer to Support Documents for Quality Certificates
Global - Refer to manufacturer's instructions for use and related User Manuals and Technical data sheets before using this products as described
Comparisons, where applicable, are made against older BD Technology, manual methods or are general performance claims. Comparisons are not made against non-BD technologies, unless otherwise noted.
Non-IVD products are For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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